Data is generally standardised and displayed in milligram per litre/cubic metre. If so, the data provided is not processed in the Brief Profile. Please see the endpoint help sections for more specific information on the sections or see the ‘Scientific properties’ header for a more complete overview. The CAS number is the substance numerical identifier assigned by the Chemical Abstract Service, a division of the American Chemical Society, to substances registered in the CAS registry database. The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. Short-term EC50 or LC50 for mammals provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of mammals in the test, generally displayed in milligram per kilo food. Therefore the quality of these names may be variable. Pimelic acid is one methylene longer than a related dicarboxylic acid, adipic acid, a precursor to many polyesters and polyamides. Release to the environment of this substance can occur from industrial use: manufacturing of the substance. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. EC50/LC50 for microorganisms provides substance information on the substance’s effect concentration or lethal concentration for 50% of the microorganisms in the test, generally displayed in milligram per litre. Solubility in organic solvents at 20°C provides substance information on the substance solubility in organic solvents in gram per litre at a temperature of 20°C. Diaminopimelic acid (DAP) is an amino acid, representing an epsilon-carboxy derivative of lysine.. DAP is a characteristic of certain cell walls of some bacteria. This section summarises the values related to the screening tests for biodegradation in water from all registered dossiers for the substance. The Brief Profile summarizes the non-confidential data on substances as it is held in the databases of the European Chemicals Agency (ECHA), including data provided by third parties. Depending on the structure of the molecule the main layer may be followed by additional layers e.g. Please see Registrants/Suppliers details. InChI=1S/C7H12O4/c8-6(9)4-2-1-3-5-7(10)11/h1-5H2,(H,8,9)(H,10,11). ECHA has no public registered data indicating whether or into which articles the substance might have been processed. Praesent et nulla orci. The Index number for each substance is in the form of a digit sequence of the type ABC-RST-VW-Y. Displayed in all cases is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as below. Relative density at 20 °C provides information on the substance relative density at 20 °C. If so, the data provided is not processed for the Brief Profile. ECHA’s Guidance Chapter R.12: Use Descriptor system of ECHA’s Guidance on information requirements and chemical safety assessment, ECHA guidance chapter R.12: Use Descriptor system of ECHA Guidance on information requirements and chemical safety assessment, Guidance on the safe use of the substance, Endocrine disrupter testing in aquatic vertebrates – in vivo, Active/Inactive (pending). If so, the data provided is not processed for the Brief Profile. For example CLH index numbers, CN numbers, deleted CAS numbers, etc. The Brief Profile is produced based on data in ECHA’s databases and maintained by the Agency, and therefore the Brief Profile as a dissemination tool falls under ECHA’s responsibility. Therefore the quality of these names may be variable. Readily biodegradable but failing the 10-day window. To confirm if a substance is covered by a specific legislative framework the official publication should be consulted.Reproduction or further distribution of this information may be subject to copyright protection. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. Henry’s law constant can be presented as different types, depending on the units chosen: H dimensionless provides substance information on the substance’s Henry’s Law Constant (dimensionless) at a temperature measured in °C and a pressure measured in Pascal. Furthermore, updates in the source data may not always result in an update of the Brief Profile. If more than one numerical result is available per endpoint, the range of results (min-max, RANGE method) will be displayed. There are four methods to aggregate and summarise data, depending on the available data and endpoint. Values are generally displayed in measured in (nano/ micro/milli)gram per kilogram (dry weight). The regulation aims improve the protection of human health and the environment from the risks that can be posed by chemicals, while enhancing the competitiveness of the EU chemical industry. Hazard to aquatic organisms provides information on the substance’s hazard assessment conclusion regarding aquatic organisms. The BPR regulatory processes identified for the Brief Profile are: Prior Informed Consent (PIC)The PIC Regulation (649/2012) entered into force on 4 July 2014. This section provides physicochemical information compiled from all automatically processable data from REACH registration dossiers that is available to ECHA at the time of generation. Processable data for summary is prioritised by test species (see list below) and subsequently further prioritised by the dose descriptor. Processable data is prioritised by the toxicity descriptor type (see list below) and subsequently further prioritised by duration (longer prioritised over shorter). If more than one IUPAC name is available from REACH registered dossiers, all IUPAC names are displayed in ‘Other names’ section of the Brief Profile. Note: Registrants can also select ‘other’ as the dose descriptor type or unit of measure. This section summarises the vapour pressure values from all registered dossiers for the substance. See ‘Summary effect on fertility oral route’, except: This section displays the values related to neurotoxicity from all registered dossiers for the substance. BOD5*100/ThOD provides substance information on the substance’s BOD5*100/ThOD values displayed in O2 (milli)gram per gram test material. If so, the data provided is not processed for the Brief Profile. Critical property indentification: Where less than 90% of the notifiers provide the same classification to derive the critical property, the border of this critical property icon is displayed as dashed. To have more information on impurities relevant to classification you can consult the C&L Inventory entry for the substance, or the disseminated registration dossier. This section provides an overview of the type of study records behind the presented results and – if applicable - data waving justifications. Dissipation half-life provides substance information on the substance’s dissipation half-life for the parent compound per second/minute/hour/day/week/month/year. Solubility in water: 50g/L (20°C). Koc at 20°C provides substance information on the substance’s Koc adsorption at a temperature 20 °C. PubChem Substance ID 24898545. Pimelic acid (Heptanedioic acid, 1,5-Pentanedicarboxylic acid, 1,7-Heptanedioic acid) originating from fatty acid synthesis pathway is a bona fide ... Quality confirmed by NMR & HPLC. Values are presented in (nano/ micro/milli)gram per litre and/or (nano/ micro/milli)molar per litre. If there are additives and impurities relevant for the substance classification, these are also indicated. Short-term EC50 or LC50 for soil microorganisms provides substance information on the substance’s effect concentration or lethal concentration (short term) for 50% of soil microorganisms in the test, generally displayed in milligram per kilo soil (dry weight). For other data an order of magnitude logic might apply; e.g. the level of agreement, in substance classification between the REACH registrants (dark blue bar) and CLP notifiers (light blue bar), as well as between the notified classifications and the approved harmonised classification. EC10 / LC10 or NOEC for microorganisms provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested microorganisms or the no observed effect concentration for microorganisms. Thirdly the display of data is prioritised by units. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. This section provides information on the recommended measures to minimise or prevent adverse effects resulting from exposure to a hazardous product, or improper storage or handling of a hazardous product. EC10 / LC10 or NOEC for freshwater plants provides substance information on the substance’s effect concentration/lethal concentration for 10% of the tested freshwater plants or the no observed effect concentration for freshwater plants. Contraindications & Blackbox Warnings data. This section summarises the Ecotoxicological information provided from all registered dossiers for the substance. The data presented in these sections has been cleaned to remove names of one character or less, or names which consist solely of punctuation or numerical characters. Pimelic acid Basic information Product Name: Pimelic acid Synonyms: RARECHEM AL BO 1093;TIMTEC-BB SBB007898;PENTAN-1,5-DICARBOXYLIC ACID;PENTANE-1,5-DICARBOXYLIC AC Henan Sunlake Enterprise Corporation is located in Henan Province , the central plain of China , which enjoys favorable geogeaphical position and convenient transportion. 'IUPAC name' is the generic field by which substance names are provided in various data submission tools. pimelic acid (3,4,5-trimethoxybenzylidene)-hydrazide 1 Product Result | Match Criteria: Product Name SMILES notations are comprised of atoms (designated by elemental symbols), bonds, parentheses (used to show branching), and numbers (used for cyclic structures). Beilstein/REAXYS Number 1210024 . Nat Rev Drug Discov. the minimum numerical value associated with the highest priority picklist item. If more than one picklist value is available per endpoint, results are displayed as concatenated distinct values, ordered by most to least commonly provided, with the % of provided values appended. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner. The regulation aims to protect human health and the environment by banning or severely restricting the production and use of persistent organic pollutants in the European Union. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight) or gram per hectare. Substances may have impurities and additives that lead to different classifications. ABC corresponds to the atomic number of the most characteristic element or the most characteristic organic group in the molecule. The availability of additional data beyond the five results displayed is indicated by (…). This section summarises the surface tension values from all registered dossiers for the substance. The purpose of the information provided under this section is to highlight in a readable format the substance hazardousness. When more than one numerical result is available per endpoint the count is displayed between square brackets. This information should not be interpreted without the help of a healthcare provider. Registrants can register their substance’s bioaccumulation properties as: Registrants can register their substance’s oral/dermal/inhalation absorption rate values in percentages. If more than one value is found for this section, the range of min-max values will be displayed here. Pre-registration allows companies to continue manufacturing and importing their. The absence of an interaction does not necessarily mean no interactions exist. 'IUPAC name' is the generic field by which substance names are provided in various data submission tools. If impurities and/or additives have been identified, an informative sentence is displayed below the graphic. The chart displays the number of matching substance classifications (hazard class, categories and hazard statements) provided by manufacturers and importers under REACH and CLP notifications, as well as whether the substance is defined under harmonised classification and labelling (CLH). The Brief Profile summarises the non-confidential data on substances as it is held in the databases of the European Chemical Agency (ECHA), including data provided by third parties. The REACH regulatory processes identified for the Brief Profile are: Persistent Organic Pollutants (POPs)The POPs Regulation (EU) 2019/1021 entered into force on 15 July 2019, repealing the previous POPs Regulation (EC) No 850/2004. The BPR addresses the placing on the market and use of biocidal products, which are used to protect humans, animals, materials or articles against harmful organisms, like pests or bacteria, by regulating the active substances contained in a biocidal product. This brief profile is covered by the ECHA Legal Notice. The ‘total tonnage’ band published does not necessarily reflect the registered tonnage band(s). Please note that the information provided in the free-text fields is not published in the brief profiles. If so, the data provided is not processed for the Brief Profile. Fusce eget lorem sed purus tempus blandit. If no data is available in the registered substance dossiers, this will be indicated by a notification stating ‘Data not provided by the registrant’. Tends to sublime. Pimelic acid has been synthesized from cyclohexanone and from salicylic acid. Displayed are the RANGES of min – max of the PRIORITISED value(s) within the five highest priority groupings of provided data. Log Pow provides substance information on the partition coefficient type Pow at a temperature measured in °C and acidity in pH. Notification – indicates that notified C&L’s have been submitted to ECHA for a substance. If so, the pressure data provided is not processed for the Brief Profile. EC10 / LC10 or NOEC for freshwater sediment provides substance information on the substance’s effect concentration/lethal concentration for 10% of the model organisms feeding off the freshwater sediment or the no observed effect concentration for of the model organisms feeding off the freshwater sediment. Therefore this does not constitute official and legally binding information. If more than one result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method). Half-life in sediment provides substance information on the substance’s half-life in sediment in seconds/minutes/hours/days/weeks/months/years at a temperature measured in °C.Note: Results without a measurement condition (temperature) are not processed for the Brief Profile. Oxidising. Data is generally displayed in milligrams per kilogram in the case of soil (dry/wet weight), or gram per hectare. If more than one numerical result is available per endpoint, the range of results (min-max) and range of experimental conditions will be presented (RANGE method).Relative density provides substance information on the relatively density (measurement units are not processed for relative density) at a temperature measured in Celsius (°C). Prioritization by the dose descriptor type: Displayed in all cases is the MOST CONSERVATIVE of the value(s) provided, ranking in the order as above, i.e. Values are generally displayed in milligrams per kilogram (dry weight). 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