Salaries, reviews and more - all posted by employees working at Hubrecht Institute. 23. Jop Kind lab. The ERC-starting grants are awarded to support up-and-coming research leaders who have recently established their own research team in Europe. Hubrecht Institute. Nederland, © Copyright 2021 Privacypolicy Hubrecht Institute. Electronic address: j.kind@hubrecht.eu. In addition, we profile the epigenetic landscapes, chromatin accessibility and transcriptome in single cells. A. Lochs †, Samy Kefalopoulou † and Jop Kind * Oncode Institute, Hubrecht Institute–KNAW and University Medical Center Utrecht, 3584 Utrecht, The researchers are each given two million euros to strengthen their research groups and continue their innovative research in the next 5 years. Cited by. Login as Dr. J. Overview; Fingerprint; Network; Research Output (8) Similar Profiles (28) If you made any changes in Pure these will be visible here soon. 2016: Group Leader, Hubrecht Institute, Utrecht, The Netherlands. Research output per year. Institute of Molecular Biotechnology, Austrian academy of science. Read more | 5 November . Other Annotations. The aim of the lab is to understand the principles governing cellular decision-making. 3,331. Sort. PHOTO: EMBL . Uppsalalaan 8 12:35. Their combined citations are counted only for the first article. Fingerprint. degree at EMBL Heidelberg and conducted her PhD research on the topic of Chromatin and Biomedical Genetics at Hubrecht Institute as a Marie-Curie fellow. To this end we employ and continuously develop novel single-cell technologies to delineate these processes with high sensitivity and accuracy. Jop, now Group Leader at … Cited by. 3 Institute of Epigenetics and Stem Cells (IES), Helmholtz Zentrum München, Munich, Germany. By Jop Kind, Hubrecht Institute. Afterwards, Alexander van Oudenaarden, Mauro Muraro and Waleed Kholosy will also give talks and elaborate on some specific applications and usage of single cell technology. Visit Kind's page. Additionally, they will investigate whether there are other, currently unknown pathways involved in repairing ICLs. Jobs. ERC-starting grant for Marvin Tanenbaum and Jop Kind Marvin Tanenbaum and Jop Kind, both group leader at the Hubrecht Institute, are awarded an ERC-starting grant. Read the new partnership agreement between Pontiac School District and the state including exhibits of data on the schools achievement gaps. She and others previously discovered that the Fanconi anemia (FA) pathway plays a crucial role in repairing ICLs. To obtain detailed insight into this trajectory, it is essential to capture all the stages with single-cell accuracy. Researchers of the Hubrecht Institute (KNAW) in Utrecht, The Netherlands, and the MRC Laboratory of Molecular Biology in Cambridge, United Kingdom, have discovered a new way in which the human body repairs DNA damage caused by a degradation product of alcohol. To study DSB-repair in single cells, we have adapted scDam&T to generate maps of DSB-repair sites in single cells. Jop Kind, Junior Group Leader at the Hubrecht Institute. Annual Scientific Meeting. Since October 2014 he is Junior Group Leader at the Hubrecht Institute. Susanne Lens Group. 2 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, The Netherlands. Publications. ). Bob Roberts 2020-06-07 16:21:36 ? ). 2 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, The Netherlands. Self-organization in embryology. Sara is now working as a computational biologist in the lab of Jop Kind at the Hubrecht Institute (Netherlands). “That allows us to make a family tree of the various epigenetic stages that preceded the choice the cell eventually made. Single cell epigenomics. About. Further, in the same cells, we also profile genome-wide chromatin states with a chromatin immunocleavage (ChIC) approach to study the relationships between DSB-repair and the local chromatin environment (Figure 3). cells Review Lamina Associated Domains and Gene Regulation in Development and Cancer Silke J. Jop Kind, Junior Group Leader at the Hubrecht Institute. Here For You During COVID-19 NEW! 13:05. EMBL alumnus Jop Kind’s research focuses on the role of DNA organisation in genome stability, cell development and disease. Jop is currently an associate professor at the Hubrecht Institute in Utrecht where his lab continues to develop new techniques to single-cell profile gene-regulation to obtain better insights into the mechanisms that govern cell fate choice in development and disease. 13:05. Technology development The Hubrecht Institute is a research institute of the Royal Netherlands Academy of Arts and Sciences (KNAW), situated on the Utrecht Science Park. Get Funding: Convey the impact of your scientific vision. The group focuses on a specific type of DNA damage called a DNA interstrand crosslink (ICL). Jop Kind. Kim L de Luca 1 , Jop Kind 2 ... 1 Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), University Medical Center Utrecht and Oncode Institute, Utrecht, The Netherlands. Protein–DNA interactions are essential for establishing cell type–specific chromatin architecture and gene expression. Publications. Jop Kind; Jurgen Marteijn; Titia Sixma; Organising Committee Oncode . A. Lochs †, Samy Kefalopoulou † and Jop Kind * Oncode Institute, Hubrecht Institute–KNAW and University Medical Center Utrecht, 3584 Utrecht, The Netherlands; s.lochs@hubrecht.eu (S.J.A.L. Merged citations. As a postdoctoral fellow in the lab of Bas van Steensel at the NKI, Jop developed novel techniques to visualize and profile single-cell spatial genome organization. Bob Roberts 2020-04-16 23:48:49? Tumorigenesis involves the continuous selective adaptation of cells from healthy tissue, to adenoma, carcinoma and eventually metastasis. Genomic regions contacting the NL are lamina associated domains (LADs), which contain thousands of genes that are lowl … We profiled these genome-lamina interactions in single cells to obtain better understanding in gene-regulation control in pre- and post-implantation embryos (Borsos et al., 2019, Nature) (Figure 2). Accurate repair of DNA damage is critical for the maintenance of genomic integrity. Online event. PhD. PMID: 31118510 PMCID: PMC6546605 Jop Kind obtained his PhD from the Radboud University in Nijmegen for his work on dosage compensation in the lab of Asifa Akhtar at the EMBL Heidelberg. Former EMBL Genome Biology PhD student, Jop Kind, has been selected as this year’s John Kendrew Young Scientist Award winner for pioneering postdoctoral work in establishing novel technologies to map chromatin domains in single cells. Follow. Chromosomal regions that associate with a thin filamentous lamina layer at the nuclear periphery are generally in an inactive transcriptional state (Guerreiro and Kind, 2019, Curr.Opin.Gen.Dev.). These topic labels come from the works of this person. EMBL alumnus Jop Kind’s research focuses on the role of DNA organisation in genome stability, cell development and disease. Additionally, they study how new cell types arise in the early development of mouse embryos, in which epigenetics plays an important role. We employ our single-cell genomic methods to study cellular trajectories on route towards malignant metastatic identities. Spatiotemporal regulation of genomic function; Hubrecht Institute. Partnership Agreement for Pontiac School District - Free download as PDF File (.pdf) or read online for free. 2016: Group Leader, Hubrecht Institute, Utrecht, The Netherlands. Credit: Jop Kind, copyright Hubrecht Institute. PMID: 32350457 DOI: 10.1038/s41596-020-0314-8 The Kind group uses a combination of single-cell genomics and microscopy methods to study the role of chromatin and epigenetics in gene-regulation control, with a focus on early mouse embryonic development and tumorigenesis. Kind’s group previously developed advanced techniques with which they can study epigenetics in a single cell and match it with the cell’s choice of identity. Oncode unites science, collaboration and valorization to create impact for patients. ‪Hubrecht Institute‬ - ‪Cited by 3,964‬ - ‪Single cell epigenomics‬ Citations per year. About. Hubrecht Institute. 2016: Group Leader, Hubrecht Institute, Utrecht, The Netherlands. Past events. 2 day event 04 - 05 Nov. Oncode - CGC Annual Conference: Basic biology meets Cancer research . Jop Kind Group. Jop Kind Group. Hubrecht Institute opens new laboratory building. This "Cited by" count includes citations to the following articles in Scholar. Publications 23. The researchers in Kind’s group will use the ERC grant to further research when and how cells make these identity choices. 13:05. 3,331. In addition, scDam&T allows determining cellular identity of cells in complex tissues -such as embryos or tumors- based on transcriptomics, in direct relation to their epigenetic regulatory landscapes (DamID). Royal Netherlands Academy of Arts & Sciences (KNAW) Phone +31 (0)30 212 1800; Email communication@hubrecht.eu; Website http://www.hubrecht.eu/ Jop Kind, group leader at the Hubrecht Institute, has been awarded the John Kendrew award. Researchers of the Hubrecht Institute (KNAW) in Utrecht, The Netherlands, and the MRC Laboratory of Molecular Biology in Cambridge, United Kingdom, have discovered a new way in which the human body repairs DNA damage caused by a degradation product of alcohol. Jobs; Jobs Tips; 11 Recession-Proof Jobs; How to Get a Job; The Perfect Resume Looks Like This; How to Write A Cover Letter; 9 Attention-Grabbing Cover Letter Examples; New On Glassdoor; Best Cities for Jobs 2020; Company Reviews . Articles Cited by. 2 Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW), University Medical Center Utrecht and Oncode Institute, Utrecht, The Netherlands. ); s.kefalopoulou@hubrecht.eu (S.K.) j.kind@hubrecht.eu. Recently, however, her group also discovered a new pathway that is involved in ICL repair; they aim to further study this newly found DNA repair route. The grant was awarded to only 327 out of 2506 applicants. Salaries, reviews, and more - all posted by employees working at Hubrecht Institute. (Jop) Kind: Active at: The Netherlands Cancer Institute: Hubrecht Institute for Developmental Biology and Stem Cell Research: Email address: If you have any questions or problems regarding login, please contact narcis@dans.knaw.nl. The research group of Knipscheer researches DNA repair: how does our genetic material remain stable and how do we prevent the development of genetic diseases such as cancer? Best Cities for Jobs 2020 NEW! To study DSB-repair in single cells, we have adapted scDam&T to generate maps of DSB-repair sites in single cells. Furthermore, as we consider technology development a core business of the group, we are continuously exploring ways to obtain richer single-cell datasets. We are interested in how cells acquire new identities and traits in lineage specification events in mice and in cancer. Award ceremony photo gallery. This is particularly difficult to study because DSBs occur randomly in the genome, thus every single cell harbors a different DSB-landscape. Read more | 11 November . Genome instability; UMC Utrecht. Nederland, © Copyright 2021 Privacypolicy Hubrecht Institute, A major interest in the group is how gene-expression control is achieved in early embryogenesis. To be announced. Over 17 years of experience in Molecular Biology, Yuva completed her MSc. Go to Website Navigation: Home; about narcis; login; Nederlands; contact. That knowledge underlines the link between alcohol consumption and cancer. In particular, the group is interested in developing high-resolution single-cell techniques which can trace dynamic chromatin changes in living cells. Chromosomal regions that associate with a thin filamentous lamina layer at the nuclear periphery are generally in an inactive transcriptional state (Guerreiro and Kind, 2019, Curr.Opin.Gen.Dev.). Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands. Jop Kind EMBL: Predoc, Akhtar group, Genome Biology, 2002-2008. Oncode, starting from a deeper understanding of the basics of cancer, works to come up with better treatments and improved diagnostics. Reads . Online event. Together with her group, Knipscheer studies the repair pathways that cells use to correct ICLs. In this conversation. Cell division & chromosome segregation; Hubrecht Institute. The Kind group researches gene regulation – how genes are turned on or off – and the influence of the packing of DNA, the epigenetics, on this mechanism. Key words: Single-cell genomics, epigenetics, spatial genome organization, bioinformatics, gene-regulation, embryogenesis, tumorigenesis. The John Kendrew Young Scientist Award (JKA) was launched in 2007 as an initiative from the EMBL Pensioner’s Association to honour EMBL’s first Director General, Sir John Kendrew (1975-1982), and to support scientists in the early stages of their career. The nuclear lamina (NL) is a thin meshwork of filaments that lines the inner nuclear membrane, thereby providing a platform for chromatin binding and supporting genome organization. Molecular mechanisms and regulation of DNA repair; Hubrecht Institute . This is harmful because it prevents the DNA from replicating and thereby makes it impossible for cells to divide. 2 day event 04 - 05 Nov. Oncode - CGC Annual Conference: Basic biology meets Cancer research. Miao-Ping Chien. Chromatin cartographer EMBL alumnus Jop Kind, this year’s John Kendrew Award winner, reflects on … Read more | 18 November . Jop Kind received his PhD from the Radboud University Nijmegen in 2008 for his work on chromatin and gene expression in the research group of Asifa Akhtar at EMBL Heidelberg. Network. Nicolas Rivron. Jop Kind Group Leader at Hubrecht Institute, Developmental Biology and Stem Cell Research Amsterdam en omgeving, Nederland Meer dan 500 connecties Isabel Guerreiro 1 , Jop Kind 2 Affiliations 1 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, The Netherlands. The grant allows her to expand her group with 4 researchers for the duration of 5 years. Wouter de Laat Group. Puck Knipscheer Group. Hubrecht Institute, NL. Annual Scientific Meeting. Hubrecht Institute, Developmental Biology and Stem Cell Research | 6,134 followers on LinkedIn. Molecular biologist dr. Jop Kind (1978) joined the Van Steensel lab as a postdoc after a highly successful PhD at the EMBL. Accurate repair of DNA damage is critical for the maintenance of genomic integrity. 7 Oncode Institute, Hubrecht Institute-KNAW and University Medical Center Utrecht, Utrecht, the Netherlands. In addition, we profile the epigenetic landscapes, chromatin accessibility and transcriptome in single cells. hubrecht.eu. Save the date for our Annual Conference! Sort by citations Sort by year Sort by title. Over 17 years of experience in Molecular Biology, Yuva completed her MSc. … Wednesday 22 July. Contact. Molecular biologist dr. Jop Kind (1978) joined the Van Steensel lab as a postdoc after a highly successful PhD at the EMBL. Network. Save the date! The Consolidator Grant is specifically awarded to researchers who have formed their own research group relatively recently and aim to further strengthen it further. Friends raise €290.800,- for Hubrecht Institute. Cell division & chromosome segregation; Hubrecht Institute. The researchers want to know when and how cells in the early embryo ‘choose’ what type of cell they will become; whether they will for example become part of the skin or rather become part of the group of cells that forms the supporting embryonic tissue such as the placenta. First article Biology meets cancer research processes with high sensitivity and accuracy whether there are other currently! Way, we profile the epigenetic landscapes, chromatin accessibility and transcriptome in single,., Munich, Germany ) awards grants to individual scientists of all nationalities and ages who perform research... Every single cell harbors a different DSB-landscape in genome architecture affect gene expression 5 years Biology... 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The impact of your scientific vision ; Mariëlle Harlé ; Yuva Oz ; Jacqueline ;! Perform groundbreaking research on the role of epigenetics in DNA double-strand repair Accurate repair of DNA in! And continuously develop novel single-cell technologies to delineate these processes with high sensitivity and accuracy Genetics!