Phthalic anhydride is the organic compound with the formula C 6 H 4 (CO) 2 O. "Phthalic Acids and Other Benzenepolycarboxylic Acids" Kirk-Othmer Encyclopedia of Chemical Technology. Inhalation Remove to fresh air. Varma, V.B. Phthalate esters are derived from phthalic anhydride by the alcoholysis reaction. If breathing is difficult, give oxygen. Phthalic acid is however easily dehydrated to form phthalic anhydride. 1989]. [4] In the 1980s, approximately 6.5×109 kg of these esters were produced annually, and the scale of production was increasing each year, all from phthalic anhydride. Molecular Weight 148.12 . TETRABROMOPHTHALIC ANHYDRIDE reacts exothermically with water. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) The solubility of phthalic anhydride was measured at 283–313 K under atmospheric pressure in ethyl acetate, n -propyl acetate, methyl acetate, acetone, 1,4-dioxane, n -hexane, n -butyl acetate, cyclohexane, and dichloromethane. InChI=1S/C8H4O3/c9-7-5-3-1-2-4-6(5)8(10)11-7/h1-4H, Except where otherwise noted, data are given for materials in their, National Institute for Occupational Safety and Health, Ullmann's Encyclopedia of Industrial Chemistry, "Development of a gel permeation chromatographic assay to achieve mass balance in cellulose acetate phthalate stability studies", https://en.wikipedia.org/w/index.php?title=Phthalic_anhydride&oldid=998651643, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License, This page was last edited on 6 January 2021, at 11:24. Logistics services are available in the United States. Phthalic anhydride is a principal commercial form of phthalic acid. Above 180 °C, phthalic anhydride re-forms. : 85-44-9 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratorychemicals, Industrial & for professional use only. Phthalic anhydride pertama kali dilaporkan pada tahun 1836 oleh Auguste Laurent. Vapor pressure is < 0.3 Pa at 20 ° C. In presence of water phthalic anhydride hydrolyzes to phthalic acid. Recrystallization of Pure Phthalic Acid. In the first of today's procedures, you will recrystallize phthalic acid, a compound that is used to make synthetic polymers such as Dacron. Chiral alcohols form half-esters (see above), and these derivatives are often resolvable because they form diastereomeric salts with chiral amines such as brucine. Manufacturer and Substance Identification Thirumalai Chemicals Limited, 25 - A SIPCOT Industrial Complex, Ranipet, 632403.Tamil Nadu, India. At room temperature, phthalic anhydride appears as crystalline needles with a characteristic, suffocating odor. At room temperature, phthalic anhydride appears as crystalline needles with a characteristic, suffocating odor. Liver and kidney injury occurred. MATERIAL SAFETY DATA SHEET (MSDS) www.lobachemie.com 17/01/2019 1/11 PHTHALIC ANHYDRIDE FOR SYNTHESIS MSDS CAS-No. Hydrolysis of anhydrides is not typically a reversible process. It is the anhydride of phthalic acid. Phthalic anhydride is the organic compound with the formula :-C6H4(CO)2O. PA is soluble in alcohol and carbon disulphide. Phthalic acid is very soluble in boiling water, 18 g/100 mL, and is much less soluble in chilled (14°C) water, 0.54 g/100 mL. Phthalic Anhydride (PA) is used as the major ingredient in the manufacture of plasticizers, unsaturated polyester resin, paint and others. University of Georgia, Athens, GA 30602. Phthalic anhydride itself is used as a monomer for synthetic resins such as glyptal, the alkyd resins, and the polyester resins. Phthalic anhydride vapour, fume or dust is a primary irritant. 1989]. Phthalic anhydride is a chemical intermediate that reacts readily and produces a broad range of products that process easily and give a wide range of performance characteristics at a low cost. Above 180 °C, phthalic anhydride re-forms. Above 180 °C, phthalic anhydride re-forms. View information & documentation regarding Phthalic anhydride, including CAS, MSDS & more. Phthalic anhydride is a versatile intermediate in organic chemistry, in part because it is bifunctional and cheaply available. [6] Phenolphthalein can be synthesized by the condensation of phthalic anhydride with two equivalents of phenol under acidic conditions (hence the name). Phthalic anhydride and maleic anhydride are commonly used in paints, varnishes and various plastic coatings. Hydrolysis of anhydrides is not typically a reversible process. Empirical Formula (Hill Notation) C 8 H 4 O 3. John Wiley & Sons, Inc. 2005]. +Add Attachment This reaction is expected to be slow, but can become vigorous if local heating accelerates it. The modern industrial variant process instead uses vanadium pentoxide (V2O5) as the catalyst in a gas-phase reaction with naphthalene using molecular oxygen. Hydrolysis of anhydrides is not typically a reversible process. [17], Phthalic anhydride is used to dehydrate short-chain nitro-alcohols to yield nitroalkenes, compounds with a high tendency to polymerize.[18]. The process begins with the reaction of phthalic anhydride with alcohols, giving the monoesters: The second esterification is more difficult and requires removal of water: The most important diester is bis(2-ethylhexyl) phthalate ("DEHP"), used in the manufacture of polyvinyl chloride compounds. The phthalic acid is somewhat soluble in water. 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